About

Pronunciation: SEK-tum-SEM-pruh
Description: Violently wounds the target; described as being as though the subject had been "slashed by a sword". Created by Severus Snape.
Seen/Mentioned: First seen in Order of the Phoenix when Snape uses it in his memory against James, but misses and only lightly cuts his cheek. Used successfully by Harry in Half-Blood Prince against Draco, and then later against the Inferi in Voldemort's Horcrux chamber, and Snape during his flight from Hogwarts. In the opening chapters of Deathly Hallows, Snape accidentally casts this curse against George Weasley in the Order's flight from Privet Drive, though George was not his intended target. It is known as a specialty of Snape's.
Etymology: Correct classical Latin sectum, past participle of verb seco, "to cut", and deformation of Latin adverb semper meaning "always".
Invented: By Severus Snape.
Notes: The spell can apparently be used against any object, but does not affect creatures that feel no pain, such as the Inferi. It may work by projecting some sort of magical cutting field/surface from the tip of the wand, a hypothesis supported by the assortment of wounds on Draco Malfoy's face and chest, produced by Harry Potter'ss wild wand-swings while using the spell against Draco. Though Snape was able to mend the wounds inflicted on Draco by this curse with ease, with "an incantation that sounded almost like song", Mrs Weasley was unable to heal her son George when his ear was severed by the curse. It was discovered in an old copy of Advanced Potion Making by Harry; Sectumsempra was invented by Snape with the words "For enemies" written next to it.

Source: Wikipedia.

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